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CD8A — TNFSF10

Text-mined interactions from Literome

Tsai et al., Arthritis Rheum 2004 (Lupus Erythematosus, Systemic) : TRAIL engagement selectively activated human CD4, rather than CD8 , T cells and augmented IFNgamma production
Bosque et al., Eur J Immunol 2005 : Additionally, the inhibition of IL-2 dependent CD4 ( + ) or CD8 ( + ) T cell blast growth upon CD3 or CD59 ligation was dependent , at least partially, on FasL and/or APO2L/TRAIL
Anel et al., Frontiers in bioscience : a journal and virtual library 2007 (Autoimmune Diseases) : However, a role of Apo2L/TRAIL as a fine tuning regulator of the immune system, especially in the regulation of CD8+ T cell activation and memory, has been also demonstrated
Bucks et al., J Immunol 2009 (Chronic Disease...) : Our findings show that Ag alone is sufficient to drive CD8 ( + ) T cell impairment, that Ag-driven loss of virus-specific CD8 ( + ) T cells is TRAIL mediated , and that removal of Ag reverses exhaustion
Brincks et al., J Immunol 2011 (Orthomyxoviridae Infections) : The current study examined the role of TRAIL in the pulmonary CD8 T cell response to a clinically significant IAV [ A/PR/8/34 ( PR8 ; H1N1 ) ] infection ( i.e., leads to observable, but limited, morbidity and mortality in wild-type [ WT ] mice )