Gene interactions and pathways from curated databases and text-mining

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IL2 — MMP3

Text-mined interactions from Literome

Meisser et al., Mol Hum Reprod 1999 : The aim of this study was to determine the effects of tumour necrosis factor alpha (TNF), interleukin-1 alpha (IL-1alpha), macrophage colony stimulating factor ( MCSF ) and transforming growth factor beta ( TGFbeta ) on the secretion of matrix metalloproteinases ( MMP ) , human chorionic gonadotrophin ( HCG ) and fetal fibronectin ( fFN ) by purified first trimester cytotrophoblastic cells (CTB) in vitro
Bamba et al., J Gastroenterol 2003 : Matrix metalloproteinase-3 secretion from human colonic subepithelial myofibroblasts : role of interleukin-17
Fleenor et al., Invest Ophthalmol Vis Sci 2003 : In the trabecular meshwork ( TM ), interleukin (IL)-1alpha is a potent inducer of MMP-3 expression
Sun et al., Connect Tissue Res 2003 (Arthritis, Rheumatoid) : Furthermore, the induction of the MMP expression and activities by interleukin-1 was suppressed by the oscillatory shear
Borghaei et al., Biochem Biophys Res Commun 2004 : A 5T/6T polymorphic site in the matrix metalloproteinase-3 (MMP-3) promoter has been identified as a repressor element involved in inhibiting induction of MMP-3 transcription by interleukin 1 ; and the 6T allele has been associated with decreased expression of MMP-3 as compared to the 5T allele
Inoue et al., Rheumatol Int 2005 (Osteoarthritis, Hip...) : Induction of vascular endothelial growth factor and matrix metalloproteinase-3 ( stromelysin ) by interleukin-1 in human articular chondrocytes and synoviocytes
Stewart et al., BMC molecular biology 2007 : Interleukin-4 inhibition of interleukin-1 induced expression of matrix metalloproteinase-3 (MMP-3) is independent of lipoxygenase and PPARgamma activation in human gingival fibroblasts
Chang et al., Rheumatol Int 2007 (Chondrosarcoma) : Activin A suppresses interleukin-1 induced matrix metalloproteinase 3 secretion in human chondrosarcoma cells
Edsparr et al., J Immunother 2010 : Effects of IL-2 on MMP expression in freshly isolated human NK cells and the IL-2 independent NK cell line YT ... We have used freshly isolated human NK cells and the IL-2 independent NK cell line, YT, to investigate the effects of IL-2 stimulation on NK cell invasion of Matrigel and on MMP expression and production
Wang et al., J Biol Chem 2010 : Importance of protein-tyrosine phosphatase-alpha catalytic domains for interactions with SHP-2 and interleukin-1 induced matrix metalloproteinase-3 expression
Benson et al., Am J Respir Cell Mol Biol 2011 : Intracellular calcium flux was augmented in response to MMP inhibition or deficiency in the same cells, and IL-2 production was reduced in CD4 ( + ) and CD8 ( + ) MMP9 ( -/- ) T cells
Park et al., Stem Cell Rev 2011 : The inhibition of MMP activity in the MSC CM by GM6001 abrogated CD25 cleavage and restored IL-2 production from the activated splenocytes
Gotoh et al., Connect Tissue Res 2013 : Extracellular ß-NAD ( + ) inhibits interleukin-1 induced matrix metalloproteinase-1 and -3 expression on human gingival fibroblasts
Mann et al., Ann Otol Rhinol Laryngol 1995 (Carcinoma, Squamous Cell...) : Supernatants of HNSCC cell lines SCC-25 and FADU stimulated with interleukin (IL)-1 alpha and IL-1 beta demonstrated modest induction of 92 kd GL production by zymogram analysis when compared with controls ; IL-2 , IL-6, and interferon-gamma had no consistent effect on MMP production