◀ Back to PARP1

PARP1 — TGFB1

Text-mined interactions from Literome

Negulescu et al., Kidney Int 2002 : The effects of TGF-beta1 on mesangial cell apoptosis, p53 phosphorylation, Bax and Bcl-2 levels, caspase 9 activity, and cleavage of PARP were examined
Yang et al., Int J Biochem Cell Biol 2004 : In addition, we observed that both TGF-beta1 induced apoptosis and PARP degradation in AML-12 cells can be completely blocked by inhibiting the protein synthesis with cycloheximide
Basoni et al., FASEB J 2005 : More importantly, TGF-beta1 greatly reduced the capacity of PMA or chemokines to activate CD11b and Rap1, a phenomenon paralleled by a loss of the Epac transcript and a reduction in 8-pCPT-2'-O-Me-cAMP mediated activation of Rap1 ... The inhibitory effect of TGF-beta1 on Rap1 activity may exert a general protective influence against aberrant transendothelial migration, thereby holding inflammatory responses in check
Filyak et al., Cell Biol Int 2007 (Adenocarcinoma) : Western-blot analysis and immunocytochemistry were used to show that doxorubicin induced PARP degradation in A549 cells, and TGFbeta-1 enhanced that action of the drug