Choi et al., Brain Res Bull 2008
(Encephalitis...) :
These results suggest that the activation of PAR1 mediates thrombin induced MMP-9 expression through the regulation of Erk1/2
Wang et al., Gynecol Oncol 2011
(Neoplasm Invasiveness...) :
Furthermore, MMP-1 and PAR1 were both significantly induced by LPA ( 20 µM ), and siRNA silencing of MMP-1 and PAR1 both significantly reduced LPA 's invasion promoting effect in DOV13 cells ( p < 0.05 )
Jaffré et al., Circulation 2012
:
In the present study, we hypothesized that ß-AR stimulation would result in MMP dependent PAR1 transactivation in cardiac cells