Gene interactions and pathways from curated databases and text-mining

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ALOX5 — IL4

Text-mined interactions from Literome

Escoubet-Lozach et al., Eur Cytokine Netw 2001 : Contrasting effect of interleukin-4 on the expression of cytosolic phospholipase A2, 5-lipoxygenase and 5-lipoxygenase activating protein in peritoneal macrophages from control and ovalbumin sensitized rats ... Thus, IL-4 acts differently on cPLA2, 5-LO and FLAP expression and AA metabolism in peritoneal macrophages depending on their resident or sensitization induced differentiated status
Rainsford et al., J Pharm Pharmacol 1996 : Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture : comparison with interleukin-1-synthesis inhibitors