◀ Back to RAC1
MYO10 — RAC1
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Gutjahr et al., Exp Cell Res 2005
(Carcinoma 256, Walker...) :
Our findings suggest an important
role of
Rac , Rho/Rho-kinase, and MLCK in controlling
myosin activity in Walker carcinosarcoma cells and show that an appropriate level of RhoA, Rac, and Rho-kinase activity is required to regulate cell polarity and migration
Weiner et al., PLoS Biol 2006
:
Hem-1 complexes are essential for
Rac activation, actin polymerization, and
myosin regulation during neutrophil chemotaxis
Pestonjamasp et al., Blood 2006
:
Using primary human neutrophils and neutrophils derived from a Rac1/Rac2-null transgenic mouse model, we demonstrate here that
Rac1 ( and not Rac2 ) is
essential for Rho and
myosin activation at the trailing edge to regulate uropod function