Gene interactions and pathways from curated databases and text-mining

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IL2 — TXN

Text-mined interactions from Literome

Koura et al., Thorax 2000 (Granuloma, Respiratory Tract...) : The expression of TRX and IL-2R in granulomas of patients with sarcoidosis has been studied to clarify a possible role for TRX in the induction of IL-2R expression
Pekkari et al., Blood 2001 : Truncated thioredoxin ( Trx80 ) induces production of interleukin-12 and enhances CD14 expression in human monocytes ... Trx80 alone induced secretion of IL-12 from CD40 ( + ) monocytes in the PBMC cultures and this effect was enhanced by IL-2
Fujiwara et al., Jpn J Pharmacol 1990 : In addition, SASP and CsA inhibited the production of interleukin 2 (IL-2) from splenocytes in these experiments
Asami et al., PloS one 2013 : TRX significantly suppressed the serum levels of interleukin-1ß ( p < 0.05 ), although neither anti-apoptotic nor anti-chemotactic effects were observed
Tagaya et al., Immunol Lett 1987 (Deltaretrovirus Infections) : Transcription of IL-2 receptor gene is stimulated by ATL derived factor produced by HTLV-I ( + ) T cell lines ... ADF enhances the expression of the IL-2-R through the augmentation of the IL-2-R mRNA in the HTLV-I ( + ) T-cell line ( ED ) as well as the NK cell line cells ( YT )
Furuke et al., Int Immunol 1995 : In addition, exogenous IL-2 could not increase ADF/TRX production in FK506 treated PBMC or in PHA blasts ... These results indicate that ADF/TRX induction in T cell activation depends on calcineurin dependent events in the early phase and that IL-2 production is not directly involved in ADF/TRX induction
Söderberg et al., Scand J Immunol 1997 (Leukemia, Lymphocytic, Chronic, B-Cell) : In clear contrast, SAC+IL-2+ Trx induced DNA synthesis of normal B cells was not inhibited by soluble anti-CD40 MoAb