UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NCI Pathway Database Signaling events mediated by HDAC Class I: NPC/RanGAP1/SUMO1/Ubc9 complex (RANGAP1-SUMO1-UBE2I-NUP62-RANBP2-NUP210-NUP214-NUP153) → Ran/GTP/Exportin 1/HDAC1 complex (RAN-XPO1-HDAC1) (modification, activates)
David et al., J Biol Chem 2002, Colombo et al., EMBO Rep 2002
Evidence: assay
NCI Pathway Database Signaling events mediated by HDAC Class I: NPC/RanGAP1/SUMO1/Ubc9 complex (RANGAP1-SUMO1-UBE2I-NUP62-RANBP2-NUP210-NUP214-NUP153) → SUMO1/HDAC1 complex (SUMO1-HDAC1) (modification, activates)
David et al., J Biol Chem 2002, Colombo et al., EMBO Rep 2002
Evidence: assay
NCI Pathway Database Sumoylation by RanBP2 regulates transcriptional repression: NPC/RanGAP1/SUMO1/RanBP2/Ubc9 complex (RANGAP1-SUMO1-RANBP2-UBE2I-NUP62-NUP210-NUP214-NUP153) → SUMO1/HDAC1 complex (SUMO1-HDAC1) (modification, activates)
David et al., J Biol Chem 2002, Colombo et al., EMBO Rep 2002
Evidence: assay
NCI Pathway Database Sumoylation by RanBP2 regulates transcriptional repression: NPC/RanGAP1/SUMO1/RanBP2/Ubc9 complex (RANGAP1-SUMO1-RANBP2-UBE2I-NUP62-NUP210-NUP214-NUP153) → Ran/GTP/Exportin 1/HDAC1 complex (RAN-XPO1-HDAC1) (modification, activates)
David et al., J Biol Chem 2002, Colombo et al., EMBO Rep 2002
Evidence: assay