Gene interactions and pathways from curated databases and text-mining

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NLK — WNT3

Text-mined interactions from Literome

Ishitani et al., Nature 1999 : These results raise the possibility that TAK1 and NLK are also involved in Wnt signalling in mammalian cells
Yamada et al., J Biol Chem 2006 : We previously reported that Nemo-like kinase (NLK) negatively regulates Wnt signaling via phosphorylation of TCF/LEF
Satoh et al., Mol Cell Biol 2007 : We previously reported that Nemo-like kinase (NLK) negatively regulates Wnt signaling via the phosphorylation of T-cell factor/lymphoid enhancer factor
Li et al., J Biol Chem 2010 : Moreover, Wnt3a stimulation led to an increase in the interaction of TAB2 with NLK and the formation of a TAK1.TAB2.NLK complex, suggesting that this TAK1-TAB2-NLK pathway may constitute a negative feedback mechanism for canonical Wnt signaling
Zanotti et al., J Cell Biochem 2012 (Wnt Signaling Pathway) : Nemo-like kinase inhibits osteoblastogenesis by suppressing bone morphogenetic protein and WNT canonical signaling
Ota et al., EMBO J 2012 : NLK positively regulates Wnt/ß-catenin signalling by phosphorylating LEF1 in neural progenitor cells ... However, the roles of NLK in Wnt/ß-catenin signalling in vertebrates remain unclear