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NGF — TXN

Text-mined interactions from Literome

Bai et al., J Neurosci 2003 : In this study, we showed that NGF induces TRX expression at protein and mRNA levels ... NGF activated the TRX gene through a regulatory region positioned from -263 to -217 bp, containing the cAMP-responsive element ( CRE ) ... NGF also induced nuclear translocation of TRX ... 2'-Amino-3'-methoxyflavone, an inhibitor of mitogen activated protein kinase kinase, which is a known inhibitor of NGF dependent differentiation in PC12 cells, suppressed the NGF dependent expression and nuclear translocation of TRX
Masutani et al., Mol Neurobiol 2004 (Neurodegenerative Diseases) : Thioredoxin is necessary for NGF signaling through CRE leading to c-fos expression and also plays a critical role in the NGF mediated neurite outgrowth in PC12 cells