Gene interactions and pathways from curated databases and text-mining

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EGFR — RASGRP3

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: RASGRP3 → EGFR (increases, EGFR Activity, RASGRP3 Activity) Stope et al., Mol Cell Biol 2004*
    Evidence: EGF induced rapid and sustained GTP loading of Rap2B, binding of Rap2B to PLC-epsilon, and Rap2B-dependent translocation of PLC-epsilon to the plasma membrane.