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EGFR — IL1A

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• MIPS Negatome - no physical interaction between proteins Interaction: IL1A — EGFR (Absence of interaction, competition binding) Bird et al., J Immunol 1989*

Text-mined interactions from Literome

Hobbs et al., J Biol Chem 2003 (Dermatitis) : Regulation of interleukin-1alpha expression by integrins and epidermal growth factor receptor in keratinocytes from a mouse model of inflammatory skin disease
Finetti et al., PloS one 2012 (Carcinoma, Squamous Cell...) : AF3485 abolished IL-1ß induced activation of the EGFR , decreasing VEGF and FGF-2 expression, and tumor mediated endothelial tube formation
Bird et al., J Immunol 1989 : The effect of IL-1 and TNF on EGF-R was compared with that of the tumor-promotor PMA which is known to `` transmodulate '' EGF-R affinity by activating protein kinase C which then phosphorylates EGF-R
Sedlak et al., Chemotherapy 1994 (Breast Neoplasms) : Interleukin (IL) 1 alpha induced the up-regulation of cell-surfac expressed epidermal growth factor (EGF) receptor on both MDA-MB-468 and BT-20 breast cancer cell lines