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ANG — NOS3
Text-mined interactions from Literome
Li et al., Cardiovasc Res 1999
(Myocardial Reperfusion Injury) :
The presence of
Ang II ( 0.3 microM ) further
enhanced these effects of anoxia-reoxygenation on
cNOS , Fas and bcl-2 expression
Patel et al., Am J Physiol 1999
:
In contrast,
ANG IV-mediated
activation of
ecNOS was abolished by the intracellular Ca ( 2+ ) chelator 1,2-bis ( 2-aminophenoxy ) ethane-N, N,N ', N'-tetraacetic acid-AM
Schultz et al., Am J Physiol Heart Circ Physiol 2002
(Arrhythmias, Cardiac...) :
LV
angiotensin II (ANG II) levels were increased ( 68 +/- 12 vs. 20 +/- 5 pg/g, P < 0.01 ) as steady-state ANG II type 1 ( AT(1) ) receptor mRNA was decreased 40 % and endothelial
nitric oxide synthase mRNA levels were
increased 2.5-fold in PO versus control dogs ( P < 0.05 )
Babaei et al., Am J Pathol 2003
:
In summary, our results demonstrate for the first time that endothelial derived NO is required for Ang1 induced angiogenesis, and that the PI3-kinase signaling mediates the activation of
eNOS and NO release in
response to
Ang1
Ryu et al., Mol Ther 2006
(Disease Models, Animal...) :
Combined gene transfer of both
ad-Ang1 and ad-VEGF165 significantly
increased cavernous angiogenesis,
eNOS phosphorylation, and cGMP expression compared with that in the groups treated with either therapy alone
Zhang et al., Neuropeptides 2008
(Brain Ischemia...) :
Medium and high-dose
Ang- ( 1-7 ) significantly
stimulated eNOS activation when compared with artificial cerebrospinal fluid ( aCSF ) treatment group at 3, 6, 12, 24, and 48h after reperfusion, however, no significant changes in eNOS expression were found between medium and high-dose Ang- ( 1-7 ) at different times after the ischemic insult
Walter et al., J Pharmacol Exp Ther 2009
(Disease Models, Animal...) :
RWPs intake significantly prevented the angiogenic process, the formation of ROS and nitrated proteins, and the expression HIF-2alpha,
eNOS , and VEGF
induced by
Ang II
Costa et al., Am J Physiol Heart Circ Physiol 2010
(Disease Models, Animal...) :
Since many ANG- ( 1-7 ) actions are enhanced in situations of increased ANG II activity, as in hypertension, in this study we investigated the in vivo
effect of
ANG- ( 1-7 ) on NOS activity and expression of endothelial (
eNOS ), neuronal ( nNOS ), and inducible NOS (iNOS) in ventricles from spontaneously hypertensive rats ( SHR ) ... Ventricular
eNOS and nNOS expression were
increased 67.4 ± 6.4 and 51 ± 10 %, respectively, by
ANG- ( 1-7 ), whereas iNOS was not changed
Staschewski et al., Neuroendocrinology 2011
:
Therefore, the LTP enhancing effect of
Ang- ( 1-7 ) was
mediated by
eNOS in females
Olson et al., Am J Physiol 1997
:
The
effects of
ANG II on
ecNOS were specific for the pulmonary artery endothelium ... The
stimulation of
ecNOS by
ANG II may act to protect the lung and maintain low pulmonary artery pressures in the renin-angiotensin model of systemic hypertension