Gene interactions and pathways from curated databases and text-mining

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ANG — NOS3

Text-mined interactions from Literome

Li et al., Cardiovasc Res 1999 (Myocardial Reperfusion Injury) : The presence of Ang II ( 0.3 microM ) further enhanced these effects of anoxia-reoxygenation on cNOS , Fas and bcl-2 expression
Patel et al., Am J Physiol 1999 : In contrast, ANG IV-mediated activation of ecNOS was abolished by the intracellular Ca ( 2+ ) chelator 1,2-bis ( 2-aminophenoxy ) ethane-N, N,N ', N'-tetraacetic acid-AM
Schultz et al., Am J Physiol Heart Circ Physiol 2002 (Arrhythmias, Cardiac...) : LV angiotensin II (ANG II) levels were increased ( 68 +/- 12 vs. 20 +/- 5 pg/g, P < 0.01 ) as steady-state ANG II type 1 ( AT(1) ) receptor mRNA was decreased 40 % and endothelial nitric oxide synthase mRNA levels were increased 2.5-fold in PO versus control dogs ( P < 0.05 )
Babaei et al., Am J Pathol 2003 : In summary, our results demonstrate for the first time that endothelial derived NO is required for Ang1 induced angiogenesis, and that the PI3-kinase signaling mediates the activation of eNOS and NO release in response to Ang1
Ryu et al., Mol Ther 2006 (Disease Models, Animal...) : Combined gene transfer of both ad-Ang1 and ad-VEGF165 significantly increased cavernous angiogenesis, eNOS phosphorylation, and cGMP expression compared with that in the groups treated with either therapy alone
Zhang et al., Neuropeptides 2008 (Brain Ischemia...) : Medium and high-dose Ang- ( 1-7 ) significantly stimulated eNOS activation when compared with artificial cerebrospinal fluid ( aCSF ) treatment group at 3, 6, 12, 24, and 48h after reperfusion, however, no significant changes in eNOS expression were found between medium and high-dose Ang- ( 1-7 ) at different times after the ischemic insult
Walter et al., J Pharmacol Exp Ther 2009 (Disease Models, Animal...) : RWPs intake significantly prevented the angiogenic process, the formation of ROS and nitrated proteins, and the expression HIF-2alpha, eNOS , and VEGF induced by Ang II
Costa et al., Am J Physiol Heart Circ Physiol 2010 (Disease Models, Animal...) : Since many ANG- ( 1-7 ) actions are enhanced in situations of increased ANG II activity, as in hypertension, in this study we investigated the in vivo effect of ANG- ( 1-7 ) on NOS activity and expression of endothelial ( eNOS ), neuronal ( nNOS ), and inducible NOS (iNOS) in ventricles from spontaneously hypertensive rats ( SHR ) ... Ventricular eNOS and nNOS expression were increased 67.4 ± 6.4 and 51 ± 10 %, respectively, by ANG- ( 1-7 ), whereas iNOS was not changed
Staschewski et al., Neuroendocrinology 2011 : Therefore, the LTP enhancing effect of Ang- ( 1-7 ) was mediated by eNOS in females
Olson et al., Am J Physiol 1997 : The effects of ANG II on ecNOS were specific for the pulmonary artery endothelium ... The stimulation of ecNOS by ANG II may act to protect the lung and maintain low pulmonary artery pressures in the renin-angiotensin model of systemic hypertension