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IL1A — PLAA
Text-mined interactions from Literome
Homaidan et al., Mediators Inflamm 1999
:
IL-1 caused concentration- and time dependent increases in the levels of PLA2 activity, and/or in the levels of
PLAP , COX-2 and PGE2
Bomalaski et al., J Immunol 1992
:
IL-1 increases phospholipase A2 activity, expression of
phospholipase A2-activating protein , and release of linoleic acid from the murine T helper cell line EL-4
Bomalaski et al., J Immunol 1995
:
Phospholipase A2-activating protein induces the synthesis of
IL-1 and TNF in human monocytes ... To further explore the mechanisms found in the inflammatory response, we examined the ability of
PLAP to
stimulate release of TNF and
IL-1 from human peripheral blood monocytes ...
PLAP , PLAP peptide, and melittin, a bee venom PLA2 activator with homology with PLAP, all
increased IL-1 and TNF production in a time- and dose dependent manner