Gene interactions and pathways from curated databases and text-mining

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IL1A — NAIP

Text-mined interactions from Literome

Casson et al., PLoS Pathog 2013 : Interestingly, whereas caspase-11 promotes IL-1ß release in response to the type IV secretion system through the NLRP3/ASC inflammasome, caspase-11 dependent release of IL-1a is independent of both the NAIP5/NLRC4 and NLRP3/ASC inflammasomes as well as TRIF and type I interferon signaling
Lage et al., Proc Natl Acad Sci U S A 2013 (Salmonella Infections) : NAIP5/NLRC4 ( neuronal apoptosis inhibitory protein 5/nucleotide oligomerization domain-like receptor family, caspase activation recruitment domain domain containing 4 ) inflammasome activation by cytosolic flagellin results in caspase-1 mediated processing and secretion of IL-1ß/IL-18 and pyroptosis, an inflammatory cell death pathway