Gene interactions and pathways from curated databases and text-mining

◀ Back to ADAM10

ADAM10 — HBEGF

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: HBEGF → ADAM10 (increases, HBEGF Activity)
    Evidence: it was recently shown that the metalloproteinase with a disintegrin domain (ADAM)-10 mediates ErbB1 transactivation after bombesin treatment
  • OpenBEL Selventa BEL large corpus: HBEGF → ADAM10 (increases, HBEGF Activity)
    Evidence: from full text - Stimulation of cells with bombesin increased the amount of shed HB-EGF in the medium. KUZ enhanced the ability of bombesin to release HB-EGF into the medium (Fig. 3 A).
  • KEGG Epithelial cell signaling in Helicobacter pylori infection: ADAM10 → HBEGF (protein-protein, activation)
  • WikiPathways Hypertrophy Model: ADAM10 → HBEGF (activation)