Gene interactions and pathways from curated databases and text-mining

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GPI — PRL

Text-mined interactions from Literome

Kulick et al., Gen Comp Endocrinol 2005 : In mammals, prolactin (PRL) secretion is regulated by vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI) ... The purpose of this study was to compare the effects of turkey PHI ( tPHI ) and turkey VIP ( tVIP ) on PRL secretion in vitro, and to study their physiological significance in vivo through active immunization against tPHI and tVIP
Ceccatelli et al., J Neuroendocrinol 1992 : There is evidence for involvement of vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine (PHI) in control of prolactin secretion
Bjøro et al., Mol Cell Endocrinol 1987 : At submaximal concentrations the effects of VIP and PHI on both cAMP accumulation and PRL secretion were additive, whereas the effects were not additive at concentrations giving maximal effects
Bjøro et al., Acta Physiol Scand 1987 (Pituitary Neoplasms) : The effect of VIP and PHI on PRL secretion in GH4C1 cells is mediated through one common receptor
Reichlin et al., Ann N Y Acad Sci 1988 : The new data reported here, and available in the literature, are interpreted to indicate that acute release of PRL in stress is probably mediated by secretion of VIP and PHI arising from a subpopulation of paraventricular cells in the tuberoinfundibular system, and that this secretion is under serotonergic control, presumably by way of the raphe nuclear projection to the hypothalamus
Kelley et al., Gen Comp Endocrinol 1988 : The effects of vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine (PHI) on the in vitro secretion of two prolactins (PRL) from the rostral pars distalis ( RPD ) and of growth hormone (GH) from the proximal pars distalis (PPD) of the pituitary of the tilapia ( Oreochromis mossambicus ) were studied
Inoue et al., Neurosci Lett 1988 : Infusion of VIP for 200 min in the concentration of 0.3 x 10 ( -7 ) M resulted in an increase in basal release of PRL and blunted PRL release induced by not only VIP but also PHI stimulation, whereas PRL release induced by TRH was not affected ... Infusion of PHI ( 0.3 x 10 ( -7 ) M, 0.7 x 10 ( -7 ) M and 10 ( -7 ) M ) for 200 min also dose-relatedly suppressed PRL release induced by not only PHI but also VIP without any change in PRL release induced by TRH
Koiwai et al., Gen Comp Endocrinol 1986 : The effects of vasoactive intestinal polypeptide (VIP) and peptide histidine isoleucine (PHI) on the in vitro secretion of prolactin (PRL) by the pituitary gland of bullfrogs ( Rana catesbeiana ) were studied
Tojo et al., Proc Soc Exp Biol Med 1985 : Involvement of peptide histidine isoleucine (PHI) in prolactin secretion induced by serotonin in rats ... The possible role of hypothalamic peptide histidine isoleucine (PHI) in prolactin (PRL) secretion induced by serotoninergic mechanisms was investigated in male rats using a passive immunization technique ... These results suggest that hypothalamic PHI is involved , at least in part, in PRL secretion induced by central serotoninergic stimulation in the rat
Ohta et al., Peptides 1985 : In in vitro studies, PRL release from superfused rat anterior pituitary cells was stimulated by PHI ( 10 ( -9 ), 10 ( -8 ) and 10 ( -7 ) M ) in a dose related manner ... The stimulating effect of PHI ( 10 ( -7 ) M ) on PRL release in vitro was as potent as that of vasoactive intestinal polypeptide (VIP) ( 10 ( -7 ) M ) and was observed even in the presence of dopamine ( 10 ( -7 ) M )
Wright et al., Prostaglandins 1981 : Somatostatin ( SRIF ), at a dose of 10 ( -6 ) M, maximally inhibited TRH induced PRL output, but failed to alter the PRL response to PGI2
Kaji et al., Life Sci 1984 : Using a perifusion system of rat anterior pituitary tissues in vitro, effluent PRL levels were also increased by 10 ( -8 ) -10 ( -7 ) M PHI
Werner et al., Neuroendocrinology 1983 : The present study demonstrates that PHI , a peptide belonging to the glucagon-secretin group and thus structurally similar to VIP, can release prolactin from dispersed rat anterior pituitary cells and also causes release of prolactin from hemipituitaries
Samson et al., Peptides 1983 : PHI induced significant, dose related stimulations of PRL release from cultured, dispersed rat pituitary cells in vitro