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IL10 — SOAT1
Text-mined interactions from Literome
Yamaoka et al., J Interferon Cytokine Res 1999
:
IL-10 inhibited IFN-gamma induced
STAT activation without newly synthesized protein
Tanuma et al., Blood 2001
:
Among cytokines tested, the inhibitory effect of PTPepsilonC is selective to IL-6- and
IL-10 induced
JAK-STAT signaling
Ding et al., J Immunol 2001
:
In this study, we characterized the differential receptor binding specificity, affinity, and Janus
kinase-STAT activation of cellular
IL-10 ( cIL-10 ) compared with viral IL-10 ( vIL-10 )
Miura et al., Apoptosis 2006
(Asbestosis...) :
These results suggested that the contact between cells and asbestos may affect the human immune system and trigger a cascade of biological events such as activation of Src family kinases, enhancement of
IL-10 expression,
STAT3 activation and Bcl-2 overexpression
Seidel et al., Proc Natl Acad Sci U S A 1995
(Carcinoma, Hepatocellular...) :
We have systematically examined the effects of the spacing between the TT and AA core half sites on the binding of the
STAT complexes
activated by IFN-gamma,
interleukin (IL) 6, granulocyte-macrophage colony stimulating factor, and IL-4
Wehinger et al., FEBS Lett 1996
:
IL-10 induces DNA binding activity of three
STAT proteins ( Stat1, Stat3, and Stat5 ) and their distinct combinatorial assembly in the promoters of selected genes ... Interaction of
IL-10 with its receptor
leads to the activation of
STAT transcription factors ... Herein we report the
IL-10 dependent simultaneous activation of three
STAT transcription factors : Stat1, Stat3, and Stat5
Yamaoka et al., J Immunol 1998
:
Taken together, these results suggest that in addition to other transcription factors,
STAT5 plays an important role in activation of monocytes by LPS, and that STAT5 is another
target for
IL-10 and Dex to inhibit COX-2 expression in activated monocytes