Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Cribbs et al., Int Immunol 2003 : QS21 and CFA induced significant IFN-gamma , IL-4 and tumor necrosis factor-alpha expression, whereas alum induced primarily IL-4 production
Kallinteris et al., J Immunother 2005 : CFA augmented the IFN-gamma response and to a lesser extent the IL-4 response
Vidyarani et al., Cytokine 2007 (Tuberculosis, Pulmonary) : 1, 25 Dihydroxyvitamin D ( 3 ) significantly suppressed IL-12p40 and IFN-gamma production in response to CFA and live M. tuberculosis with a maximum suppression at 10 ( -7 ) M concentration ( p < 0.0001 )
Selvaraj et al., J Clin Immunol 2008 (Genetic Predisposition to Disease...) : We studied the influence of VDR promoter ( Cdx-2 and A1012G ), 3 ' untranslated region ( Apa I, Bsm I, and Taq I ) and start codon ( Fok I ) polymorphisms on 1,25 ( OH ) ( 2 ) D ( 3 ) -modulated IL-12p40, IFN-gamma , IL-10, and IL-5 response to live Mycobacterium tuberculosis and its culture filtrate antigen (CFA) in 60 normal healthy subjects and 51 pulmonary tuberculosis patients
Castro-Matteotti et al., Mycopathologia 2008 (Mycetoma...) : In mice, CFA and three of the protein fractions ( P3, P4 and P5 ) induced significant IFN-gamma production in the infected group ... In humans, only the CFA induced IFN-gamma production and cell proliferation in the group of patients with actinomycetoma
Beck et al., Cell Immunol 1989 : The low specific and lack of nonspecific IgE formation by mice injected with OVA in cFA may be the result of cFA induced interferon-gamma (IFN-gamma) production because IFN-gamma has been shown to stimulate IgG2a and inhibit IgE secretion in vitro