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IFNG — PIGR

Text-mined interactions from Literome

Loman et al., Immunology 1999 : IFN-gamma and IL-4 induced similar maximal expression of pIgR , but IFN-gamma enhanced sIgA release more than IL-4
Rincheval-Arnold et al., Mol Cell Endocrinol 2002 : In contrast, nothing is known of the effects of IFN-gamma on pIgR gene expression in the mammary gland ... We report here that IFN-gamma strongly increased pIgR mRNA levels through a direct effect on mammary epithelial cells
Piskurich et al., Mol Immunol 1993 (Colonic Neoplasms) : We studied the mechanism by which interferon-gamma (IFN-gamma) induces pIgR expression in HT-29.74 cells, a subclone of the HT-29 cell line selected for high concns of pIgR ... This assay was used to determine if induction of pIgR by IFN-gamma is mediated by accumulation of pIgR mRNA ... These results suggest that induction of pIgR expression by IFN-gamma involves an increase in steady-state concns of pIgR mRNA via a protein synthesis dependent mechanism
Piskurich et al., Mol Immunol 1997 : Transcriptional regulation of the human polymeric immunoglobulin receptor gene by interferon-gamma ... Interferon-gamma (IFN-gamma) , a major regulator of pIgR expression, has been shown to increase pIgR mRNA levels in HT-29 human colon carcinoma cells ... It is now shown that IRF-1 is not detected in nuclear extracts from HT-29 cells stimulated with IFN-gamma in the presence of cycloheximide, suggesting that de novo synthesis of IRF-1 is required for induction of pIgR transcription by IFN-gamma