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IL6 — SRC

Text-mined interactions from Literome

Salinthone et al., Am J Physiol Gastrointest Liver Physiol 2004 (Inflammation) : Expression of IL-1beta, IL-6 , IL-8, and COX-2 mRNA was reduced by 30 microM PP1, an Src family tyrosine kinase inhibitor, and by 25 microM SB-203580, a p38 MAPK inhibitor
Hausherr et al., Oncogene 2007 (Multiple Myeloma) : IL-6-treatment of INA-6 cells induced the kinase activities of Fyn, Lyn and Hck, but not Src , and the IL-6 induced SFK activities were inhibited by peptide 18AD
Schlaepfer et al., J Biol Chem 2007 : Inhibition of Src protein-tyrosine kinase activity or mutation of Src phosphorylation sites on FAK ( Tyr-861 or Tyr-925 ) did not affect TNFalpha stimulated IL-6 expression
Chiu et al., Mol Immunol 2008 : Thrombin induced IL-6 production in human synovial fibroblasts is mediated by PAR1, phospholipase C, protein kinase C alpha, c-Src , NF-kappa B and p300 pathway
Suh et al., J Cell Physiol 2009 : In addition, IL-6 increased EGFR/src/FAK , PI3K/Akt phosphorylation and 2-DG uptake as well as GLUT-2 protein expression, which were blocked by AG 1478 ( EGF receptor inhibitor ), PP2 ( src family of tyrosine kinase inhibitor ), PI3K-specific siRNA, and a Akt inhibitor