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MAP2K1 — PGF
Text-mined interactions from Literome
Yoshida et al., Mol Cell Endocrinol 2005
:
Tiludronate attenuated the phosphorylation of both Raf-1 and
MEK1/2 induced by
PGF2alpha
Hanai et al., Horm Metab Res 2006
:
PGF2alpha stimulated phosphorylation of Raf-1,
MEK1/2 and p44/p42 MAP kinase were suppressed by minodronate
Mohammed et al., Am J Physiol Lung Cell Mol Physiol 2007
(Mechanotransduction, Cellular) :
The stretch induced
PlGF production and NO synthesis were
attenuated by PD98059, a specific
mitogen activated protein kinase kinase-1 and -2 inhibitor
Xu et al., Mol Pharmacol 2008
(MAP Kinase Signaling System) :
FP receptor stimulation by
PGF ( 2alpha )
induced the phosphorylation of C-Raf,
MEK1/2 , and extracellular signal regulated kinases 1 and 2, consistent with the activation of a MAP kinase signaling cascade
Chen et al., Endocrinology 1998
:
Additionally, both
PGF2alpha ( 1 microM ) and PMA ( 20 nM )
stimulated phosphorylation of Raf-1,
MEK1 , and p42mapk in 32P labeled cells