Davis-Smyth et al., J Biol Chem 1998
:
Domain 2 residues Arg159, Glu208 and His223-Arg224 ( together ) affect both VEGF and PlGF binding, while Glu137, Lys171, His223, and Arg224 affect PlGF but not VEGF
Alonso et al., J Auton Pharmacol 1998
:
The inhibitory effect of L-Arg on the PGF2alpha- and K+-induced contractions was completely reversed by the NOS inhibitor, NG-monomethyl-L-arginine ( L-NMMA, 0.1 mM )