Gene interactions and pathways from curated databases and text-mining

◀ Back to LEP

KISS1 — LEP

Text-mined interactions from Literome

Smith et al., J Neuroendocrinol 2006 : First, we examined whether leptin regulates the expression of Kiss1 by comparing levels of KiSS-1 mRNA in the arcuate nucleus among groups of mice having different circulating levels of leptin : ( i ) wild-type (WT); (ii) leptin-deficient ob/ob ; and ( iii ) ob/ob mice treated with leptin
Luque et al., Endocrinology 2007 (Obesity) : Moreover, leptin , but not insulin or IGF-I, stimulated KiSS-1 mRNA expression in the mouse hypothalamic cell line N6
Morelli et al., J Sex Med 2008 : In addition, leptin ( 1 nM, 24 hours ), an adipocyte derived hormone acting on the reproductive axis, significantly increased KiSS-1/GPR54 expression in FNC-B4