Gene interactions and pathways from curated databases and text-mining

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MMP2 — NOS3

Text-mined interactions from Literome

Gurjar et al., Arterioscler Thromb Vasc Biol 1999 : eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity
Chen et al., Tokai J Exp Clin Med 2008 (Plaque, Atherosclerotic) : Activation of inducible nitric oxide synthase increases MMP-2 and MMP-9 levels in ApoE-knockout mice
Koo et al., Korean circulation journal 2011 : These results suggest that elevated eNOS expression may be responsible for MMP-2 activation
Souza-Pinto et al., J Biomed Mater Res A 2013 (Inflammation) : Inducible nitric oxide synthase inhibition increases MMP-2 activity leading to imbalance between extracellular matrix deposition and degradation after polypropylene mesh implant
Qin et al., Journal of biomedical research 2010 : In addition, eNOS significantly reduced the mRNA levels of MMP-2 and MMP-9