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HRAS — MMP13
Text-mined interactions from Literome
Lee et al., Int J Cancer 2006
(Neovascularization, Pathologic) :
Our results suggested that activation of
MMP-13 as well as MMP-9
induced by
H-Ras is involved in angiogenesis and with farnesyl transferase inhibitors, in part, exerts their anticancer effects
Kang et al., Oncol Rep 2009
(Breast Neoplasms...) :
Taken together, this study clearly demonstrated the inhibitory effect of simvastatin and lovastatin on
H-Ras induced invasion,
MMP expression and signal transduction in MCF10A breast epithelial cells, providing supporting rationale for future statin trials as a therapeutic intervention to regulate breast cancer metastasis
Liao et al., Mol Med 2012
(Neoplasm Metastasis...) :
CSE1L overexpression also triggered microvesicle generation, and CSE1L knockdown diminished
v-H-Ras induced microvesicle generation,
matrix metalloproteinase (MMP)-2 and MMP-9 secretion and metastasis of B16F10 melanoma cells