◀ Back to IRF6

IRF6 — KCNH4

Text-mined interactions from Literome

Sheth et al., Surgery 2001 (MAP Kinase Signaling System) : Elk-1 phosphorylation ( ERK target ) is significantly increased by LPS alone and by inhibition of the p38 pathway during LPS stimulation
Simi et al., J Neurochem 2005 : We found that ( 1 ) LPS induced c-fos mRNA levels were sensitive to p38 mitogen activated protein kinase ( MAPK ) inhibitors but not to mitogen-activated/extracellular signal regulated kinase ( ERK ) or calcium-calmodulin dependent kinase inhibitors, ( 2 ) LPS activated both serum response element ( SRE ) and cyclic AMP/calcium response element ( CRE ) -driven luciferase reporters in transient transfection assays, ( 3 ) LPS induced the phosphorylation of Elk1 CRE binding protein ( CREB ) /activated transcription factor-1 (ATF-1) and the activation of GAL4-Elk1 and GAL4-CREB chimeric proteins, and ( 4 ) mutation of both SRE and CRE elements was necessary and sufficient to completely abolish LPS induction of a rat c-fos proximal promoter-luciferase reporter