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NPY6R — TNF

Text-mined interactions from Literome

Jung et al., J Clin Immunol 2005 (MAP Kinase Signaling System...) : Further, the Src inhibitor PP2 inhibited the release of TNF-alpha but enhanced IL-10 release, suggesting the differential regulation of Src kinase in upstream signaling
Smolinska et al., Mol Immunol 2008 : Here we show that the pyrazolo pyrimidine compound PP2 , a selective inhibitor of Src family kinases (SFK), can inhibit LPS induced TNF production as well as a number of other inflammatory cytokines ... PP2 suppressed the activity of both TNF and IL-10 driven reporter genes, suggesting that this activity is mediated at the level of transcription
Cheon et al., Exp Mol Med 2007 (MAP Kinase Signaling System) : On the other hand, PP2 , a c-Src specific inhibitor, did not affect TCDD induced TNF-alpha expression
Ohama et al., J Biol Chem 2010 : Transient expression of either VCP/p97 or PP2Ac was sufficient to elevate levels of the dual specificity phosphatase DUSP1, reduce p38 MAPK activation, and suppress tumor necrosis factor-alpha release