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CCR4 — CCR5

Pathways - manually collected, often from reviews:

• Reactome Reaction: CCR4 → CCR5 (reaction) Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Text-mined interactions from Literome

Imamura et al., Clin Exp Immunol 2005 (Behcet Syndrome) : In the intestinal samples, CCR5 was detected in all the cases with BD, whereas Th2 related CCR3 and CCR4 were detected randomly, mainly in the cases with inactive BD and those receiving large amounts of prednisolone, indicating the Th1-dominant immune responses in the intestinal lesions
Morimoto et al., J Leukoc Biol 2005 : Although the levels of surface CCR4 expression were not increased after the subsequent reculture in the absence of TCR stimulation, CCR4 responsiveness was induced in this stage of Th2 cells
Moreno et al., Hepatology 2005 (Drug-Induced Liver Injury) : In conclusion, CCR5 deficiency exacerbates T-cell mediated hepatitis, and leads to increased levels of CCR5 ligands and a more pronounced liver mononuclear infiltrate, suggesting that CCR5 expression can modulate severity of immuno mediated liver injury
Pham et al., J Neuroimmunol 2012 (Brain Neoplasms...) : CCL5, CCR1 and CCR5 in murine glioblastoma : immune cell infiltration and survival rates are not dependent on individual expression of either CCR1 or CCR5