UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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PCNA — YWHAG

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Intact Interaction: Complex of 73 proteins (association, tandem affinity purification) Xirodimas et al., EMBO Rep 2008
IRef Intact Interaction: Complex of 400 proteins (association, cross-linking study) Humphries et al., Science signaling 2009
IRef Intact Interaction: Complex of 156 proteins (association, anti tag coimmunoprecipitation) Lau et al., Cell 2012

Text-mined interactions from Literome

Lacey et al., Proc Natl Acad Sci U S A 1999 : Cyclin dependent kinase control of centrosome duplication
Arnaud et al., Chromosoma 1998 : In vertebrates, Plks participate in centrosome maturation and spindle assembly, as well as the activation of the Cdk1/cyclin B complex