Meyer zu Schwabedissen et al., Drug Metab Dispos 2006
(MAP Kinase Signaling System) :
In each cell type, EGF increases expression of ABCG2 by activation of mitogen activated protein kinase cascade via phosphorylation of extracellular regulated kinase (ERK)1/2 and c-jun NH-terminal kinase/stress activated protein kinase ( JNK/SAPK ) ... Taken together, our data show regulation of ABCG2 expression by EGF de Boussac et al., Biochem Biophys Res Commun 2012
(Carcinoma, Hepatocellular...) :
ABCG2 mRNA expression was also increased by EGF , oxidative stress or activation of the aryl hydrocarbon receptor, while decreased by TGFb