Gene interactions and pathways from curated databases and text-mining

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IRF6 — MAL

Text-mined interactions from Literome

Altavilla et al., Cardiovasc Res 2002 (Shock, Septic) : Moreover we studied in LPS stimulated ( 50 microg ml(-1) ) peritoneal macrophages ( Mphi ), NF-kappaB activation, cytoplasmic IkappaB-alpha degradation, the message for TNF-alpha, and TNF-alpha and MAL levels ... In addition, in vitro LPS stimulation ( 50 microg ml(-1) ) significantly induced NF-kappaB activation and cytoplasmic IkappaBalpha degradation in Mphi, enhanced TNF-alpha mRNA levels and increased Mphi TNF-alpha and MAL
Sacre et al., J Immunol 2007 : Previously, we showed that MyD88 or Mal dominant negative constructs did not inhibit LPS induction of cytokines in primary human M-CSF derived macrophages