Gene interactions and pathways from curated databases and text-mining

◀ Back to TNF

TNF — TUFM

Text-mined interactions from Literome

Park et al., Cytokine 2002 : Here we focused on the p43 induced TNF production and determined its responsible signal pathway ... The p43 induced TNF production was mediated by the activation of MAPK family members, ERK and p38 MAPK, and by IkappaB degradation leading to the activation of NFkappaB ... The inhibitors for protein kinase C ( PKC ) and phospholipase C (PLC) prevented the p43 induced TNF production ... Together, the p43 induced TNF production was controlled by NFkB, p38 MAPK, and ERK that is dependent on the activities of PLC and PKC
Park et al., Am J Pathol 2005 : In skin wound regions from mice, tumor necrosis factor-alpha induced p43 expression and secretion from macrophages recruited to the site