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ANG — TNF

Text-mined interactions from Literome

Niimi et al., Jpn J Pharmacol 2002 : The present study was designed to clarify the role of angiotensin II (Ang II) in modulating renal tumor necrosis factor (TNF)-alpha and interleukin-6 (IL-6) production and to investigate the effect of one dose of Ang II inhibitor on cytokines production following lipopolysaccharide (LPS) to cause endotoxemia
Kalra et al., Circulation 2002 : Previous studies suggest that angiotensin II (Ang II) upregulates the expression of tumor necrosis factor (TNF) in nonmyocyte cell types ; however, the effect of Ang II on TNF expression in the adult mammalian heart is not known
Nakamura et al., Cytokine 2002 : However, following the addition of indomethacin or H-89, Ang II significantly increased TNF-alpha release, transcriptional activity, and mRNA level
Pizurki et al., Br J Pharmacol 2003 : In contrast to its ability to counteract the increase in monolayer permeability brought about by various inflammatory agents, Ang1 did not affect the ability of histamine, PAF, or tumor necrosis factor-alpha to stimulate PMN adherence to EC
Shcheglovitova et al., Bull Exp Biol Med 2003 : Angiogenin isolated from cow milk induces the production of cytokines IL-1beta, IL-6, and TNF-alpha in human leukocytes ; the level of production of each cytokine depends on the concentration of the preparation, and the dynamics of production depends on the time from the beginning of induction
DeBusk et al., Arthritis Rheum 2003 (Arthritis, Experimental...) : Primary cultured endothelial cells and synoviocytes were used to study tumor necrosis factor alpha (TNF alpha) induced Tie2 and Ang1 expression
Ferreri et al., Curr Pharm Des 2004 (Diabetes Mellitus) : Our initial studies on renal cyclooxygenase (COX)-2 expression and activity addressed the critical role of angiotensin II (Ang II) in increasing tumor necrosis factor alpha (TNF) that eventuated in expression of COX-2 in the medullary thick ascending limb ( mTAL ) of the nephron
Miura et al., J Pharmacol Sci 2006 : Alacepril, CV-11974, and spironolactone significantly reduced the enhanced production of MCP-1 and TNF-alpha induced by exogenous Ang II
Wei et al., Am J Physiol Endocrinol Metab 2008 (Insulin Resistance) : Moreover, ANG II treatment of L6 myotubes induced NF-kappaB activation and TNF-alpha production and decreased insulin stimulated Akt activation and GLUT-4 glucose transporter translocation to plasma membranes
Rosa et al., Inflamm Res 2012 : Ang II, after at least 72 h of repeated treatment, increased basal TNFA gene expression and cytokine release with a biphasic pattern and maximum response at 10 nM
Yu et al., Int J Mol Med 2013 : TMP inhibited Ang II stimulated TNF-a protein secretion and mRNA expression in the cardiomyocytes ... Furthermore, the inhibition of NF-?B by the specific inhibitor, pyrrolidine dithiocarbamate ( PDTC ), markedly attenuated the Ang II induced increase in [ 3H ] leucine incorporation, ß-MHC mRNA expression and TNF-a protein secretion ... Our findings suggest that TMP inhibits Ang II induced cardiomyocyte hypertrophy and TNF-a production through the suppression of the NF-?B pathway, which may provide new insight into the mechanisms underlying the protective effects of TMP in heart diseases
Ferreri et al., Am J Physiol 1998 : The effects of angiotensin II (ANG II) on tumor necrosis factor-alpha (TNF) production were determined in freshly isolated tubules from the medullary thick ascending limb ( MTAL ) ... We conclude that ANG II regulates TNF production in the MTAL, an interaction that affects 86Rb uptake via an eicosanoid dependent mechanism in this nephron segment