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CPD — PRL
Text-mined interactions from Literome
Too et al., Endocrinology 2001
(Neoplasms) :
CPD-N expression ( 7.5-kb messenger RNA ) was
stimulated by
PRL ( 10 ng/ml ) and/or by interleukin-2 ( 24 U/ml ) in Nb2-11C and Nb2-Sp cells
Abdelmagid et al., Endocrinology 2008
(Breast Neoplasms) :
We have reported that
prolactin (PRL) regulated
CPD mRNA levels in MCF-7 breast cancer cells ... This study examined
PRL/17beta-estradiol ( E2 )
regulation of
CPD/CPM expression, and the role of CPD in NO production for survival of MCF-7 cells ...
PRL/E2 increased
CPD mRNA levels by 3- to 5-fold but had no effect on CPM ... In summary,
PRL/E2 induced cell-surface
CPD released Arg from extracellular substrates, increased intracellular NO, promoted survival and inhibited apoptosis of MCF-7 cells
Thomas et al., Prostate 2012
(Adenocarcinoma...) :
This study determined the
effects of testosterone ( T ) and
prolactin (PRL) on
CPD expression, and the role ( s ) of CPD in NO production and survival of prostate cancer ( PCa ) cells ... The
effects of
PRL/T on
CPD/NO levels in PC-3, MDA-PCa-2b, and 22Rv1 cells were also evaluated