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BCL6 — TCF3
Text-mined interactions from Literome
Glasgow et al., Neurochem Res 2000
(Neurodegenerative Diseases) :
Key in these cascades is the
activation of the caspase and
Bcl-family of proteins by the NF-kappaB
transcription factor
Vasanwala et al., J Immunol 2002
(Cell Transformation, Neoplastic) :
Expression of the Blimp-1
transcription factor , which is critical for promoting B cell differentiation into plasma cells, is
repressed by
BCL-6
Kusam et al., J Immunol 2003
:
Since the promoters for Th2 cytokines such as IL-4, IL-5, IL-10, and IL-13 do not contain consensus BCL-6 DNA binding sites, we investigated whether
BCL-6 might
regulate the GATA-3
transcription factor that activates the expression of multiple Th2 cytokines
Xie et al., Crit Rev Immunol 2006
:
However,
TCF-1 and ROR gamma t by themselves are not
sufficient to stimulate
Bcl-xL expression
Gyamfi et al., J Pharmacol Exp Ther 2008
(Inflammation...) :
Furthermore, signal transducer and activator of
transcription factor ( STAT ) 3 and associated
Bcl-xL induction was observed in ethanol fed wild-type mice but not in ethanol fed hepatocyte RXRalpha-deficient mice
Ochiai et al., Int Immunol 2008
:
Regulation of the plasma cell
transcription factor Blimp-1 gene by Bach2 and
Bcl6