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ID2 — IGF2
Text-mined interactions from Literome
Belletti et al., J Biol Chem 2001
:
Specifically, we found that the
IGF-IR activated by its ligand was a strong
inducer of
Id2 gene expression in 32D murine hemopoietic cells ... The role of PI3K activity in the
up-regulation of
Id2 gene expression by the
IGF-IR was confirmed by different methods and in different cell types
Prisco et al., Mol Cell Biol 2001
:
These results indicate that in 32D cells, the
IGF-IR regulates the expression of the
Id2 gene and that this regulation is modulated by both positive and negative signals
Wahdan-Alaswad et al., Cancer Res 2010
(Prostatic Neoplasms) :
Similarly,
IGF-I suppressed BMP4 induced transcription of the Id1,
Id2 , and Id3 genes that are crucially involved in prostate tumor progression through PI3K dependent and mTORC1/2 dependent mechanisms