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FGF2 — NPY
Text-mined interactions from Literome
Barnea et al., Endocrinology 1993
:
bFGF ( 0.1 nM )
induced a approximately 2-fold increase in
NPY production under basal conditions as well as after For + PMA ( p < 0.001 vs control )
Takei et al., Brain Res Mol Brain Res 1996
:
In contrast,
basic fibroblast growth factor , cilliary neurotrophic factor and interferon-gamma
had no effect on
NPY expression
Ji et al., Regul Pept 1996
:
Using immunohistochemistry and in situ hybridization the in vivo
effects of acidic and
basic fibroblast growth factor ( aFGF, bFGF ), and of nerve growth factor (NGF) on the expression of galanin,
neuropeptide Y (NPY) and substance P in axotomized dorsal root ganglia ( DRGs ) were examined ... In vivo administration of aFGF counteracted the axotomy induced increase in galanin and NPY, whereas
bFGF only
suppressed NPY upregulation
Barnea et al., Regul Pept 1998
:
The
effects of brain derived neurotrophic factor ( BDNF, 50 ng/ml ),
basic fibroblast growth factor (bFGF) , substance P ( 1 microM ), forskolin ( 10 microM ), or phorbol 12-myristate-13-acetate ( PMA, 20 nM ) on
NPY-IR production was tested on rat and human primary astrocyte cultures ... Of these agents, PMA and
bFGF markedly
induced NPY-IR production by rat as well as human astrocytes, forskolin induced NPY-IR production by human but not rat astrocytes, and neither BDNF nor substance P induced NPY-IR production by rat or human astrocytes