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HSPA5 — RELA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Yamazaki et al., J Immunol 2009
:
Following the degradation of
GRP78 , transient activation of
NF-kappaB was
observed with a peak at 6-12 h ; the activation subsided within 24 h despite the continuous absence of intact GRP78 ... These results suggested that loss of
GRP78 by SubAB
leads to transient phosphorylation of Akt and consequent activation of
NF-kappaB through the ATF6 branch of the UPR
Lin et al., Cancer Res 1998
:
Brefeldin A, an agent that disrupts protein transport from the endoplasmic reticulum to the Golgi, induces the expression of
GRP78 and the
activation of
nuclear factor (NF)-kappaB in cells