◀ Back to PHKA2
PHKA2 — VAV1
Text-mined interactions from Literome
Gao et al., Biochem J 2009
:
These results indicate that
Pyk2 is a critical signalling molecule downstream of beta3 integrin tyrosine phosphorylation and
mediates Vav1 recruitment to accomplish actin reorganization necessary for adhesion
Kamen et al., J Immunol 2011
(Abscess...) :
The absence of
Pyk2 resulted in a severe reduction in paxillin and
Vav phosphorylation following integrin ligation, which likely accounts for the poor degranulation and cell migration