Gene interactions and pathways from curated databases and text-mining

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PHKA2 — VAV1

Text-mined interactions from Literome

Gao et al., Biochem J 2009 : These results indicate that Pyk2 is a critical signalling molecule downstream of beta3 integrin tyrosine phosphorylation and mediates Vav1 recruitment to accomplish actin reorganization necessary for adhesion
Kamen et al., J Immunol 2011 (Abscess...) : The absence of Pyk2 resulted in a severe reduction in paxillin and Vav phosphorylation following integrin ligation, which likely accounts for the poor degranulation and cell migration