Gene interactions and pathways from curated databases and text-mining

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APC — TLR4

Text-mined interactions from Literome

Schwarz et al., Eur J Immunol 2003 : Stimulation of Toll-like receptors ( TLR ) by pathogen derived compounds leads to activation of APC , facilitating the induction of protective immunity
Barr et al., Eur J Immunol 2007 : TLR mediated stimulation of APC : Distinct cytokine responses of B cells and dendritic cells
Singh et al., J Immunol 2007 (Autoimmune Diseases) : Finally, we could replace the requirement for TLR mediated APC activation in soluble-Ag induced T cell expansion and differentiation, by maintaining the Ag depot in vivo using repeated immunizations
Fujimi et al., J Leukoc Biol 2009 (Burns) : This report addresses the potential contribution of dendritic cells ( DC ) to changes in adaptive immune function after injury by specifically measuring injury induced changes in splenic DC numbers and subsets, cell-surface markers, TLR responses , and APC function
Tewary et al., Blood 2010 : GNLY induced APC recruitment and activation required the presence of Toll-like receptor 4