Gene interactions and pathways from curated databases and text-mining

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NOS2 — PTGES

Text-mined interactions from Literome

Devaux et al., J Immunol 2001 : Lipopolysaccharide induced increase of prostaglandin E ( 2 ) is mediated by inducible nitric oxide synthase activation of the constitutive cyclooxygenase and induction of membrane associated prostaglandin E synthase
Xiao et al., PloS one 2012 : In summary, our data show that mPGES-1 , but not mPGES-2 or c-PGES isomerase, mediates LPS induced late-phase burst of PGE ( 2 ) generation, and regulates LPS induced iNOS expression in BMDM