◀ Back to EPHB2
EPHB2 — MUC8
Text-mined interactions from Literome
Kim et al., J Korean Med Sci 2002
(MAP Kinase Signaling System) :
PD98059 (
MEK/ERK inhibitor )
suppressed IL-1beta mediated MUC2 gene expression and
mucin secretion, while SB203580 ( p38 inhibitor ) did not
Alcaide et al., Eur J Immunol 2004
(Chagas Disease) :
Furthermore, AgC10 inhibition must lie upstream in the MAPK activation pathway by LPS, since this
mucin also
inhibited extracellularly regulated kinase (ERK) and Jun kinase (JNK)activation
Cho et al., J Biol Chem 2005
(MAP Kinase Signaling System) :
Here, we show that
ERK mitogen activated protein kinase is
essential for PGE2 induced
MUC8 gene expression in normal human nasal epithelial cells and that p90 ribosomal S 6 protein kinase 1 (RSK1) mediates the PGE2 induced phosphorylation of cAMP-response element binding protein
Lim et al., American journal of translational research 2009
:
In the present study, we showed that positive
regulation of MUC5AC
mucin expression by
ERK1/2 is dependent on Ras-Raf-1 signaling pathway, whereas the negative regulation of MUC5AC expression by JNK1/2 is dependent on MEKK3 ...
Ras-Raf1-ERK1/2 dependent AP-1 activation positively
regulates MUC5AC
mucin induction by S. pneumoniae, whereas MEKK3-JNK1/2 dependent AP-1 activation negatively regulates it