Gene interactions and pathways from curated databases and text-mining

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PAM — TLR4

Text-mined interactions from Literome

Dasu et al., Atherosclerosis 2009 (Inflammation) : Pam3CSK4 and LPS induced TLR2 and TLR4 expression at mRNA and protein levels are inhibited by candesartan both in vitro and in vivo
Nerren et al., Vet Immunol Immunopathol 2010 (Poultry Diseases) : The aim of the present study was to gain better insight into the nature of the ligand for TLR15 by characterizing gene expression patterns of TLR15 by heterophils in response to numerous bacterial derived TLR agonists LPS, flagellin, CpG oligodeoxynucleotides, lipotechoic acid (LTA), peptidoglycan ( PGN ), and Pam3CSK4 (PAM) , stimulation with live Salmonella enterica serovar Enteritidis ( SE-used as a positive control ), chicken isolates of Escherichia coli ( EC ) and Enterococcus gallinarum ( EG ), the equine-specific pathogen Rhodococcus equi, and stimulation with heat killed, and formalin killed SE, EC, and EG
Lim et al., J Immunother 2012 (Neoplasms) : Combined TLR Stimulation With Pam3Cys and Poly I: C Enhances Flt3-Ligand Dendritic Cell Activation for Tumor Immunotherapy
Liu et al., Mol Cell Biochem 2013 (MAP Kinase Signaling System) : The aim of our study is to investigate the role of RP105 in mouse macrophages activation of TLR4 and TLR2 signaling by lipopolysaccharides (LPS) and Pam3CysSerLys4 ( Pam3CSK4 ) alone or in combination, and the interaction between TLR2 and TLR4 signaling through RP105