Gene interactions and pathways from curated databases and text-mining

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CD40LG — NOS2

Text-mined interactions from Literome

Müerköster et al., Clin Cancer Res 2000 (Neoplasms, Experimental) : We now show that the CD40-CD40L ( CD154 ) interaction is involved in the induction of inducible nitric oxide synthase (iNOS) expression during adoptive immunotherapy ( ADI ) ... Blocking of CD40L in vivo at days 5 and 20, when all iNOS+ cells express CD40, leads to significantly reduced CD40 and iNOS expression as well as to a marked inhibition of the therapeutic effect
Sommer et al., Vet Immunol Immunopathol 2009 : In contrast, MDM cells infected with MAP failed to up-regulate expression of iNOS and IL-12p40 genes in response to CD40L