Gene interactions and pathways from curated databases and text-mining

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CA1 — EPO

Text-mined interactions from Literome

Miller et al., J Biol Chem 1999 : Transfection of CHO cells with pTracer encoding wild-type Epo-R, but not pTracer alone, resulted in an Epo induced [ Ca]i increase that was abolished in cells transfected with Epo-R F8 ( all eight cytoplasmic tyrosines substituted ) ... Transfection with carboxyl-terminal deletion mutants indicated that removal of the terminal four tyrosine phosphorylation sites, but not the tyrosine at position 479, abolished Epo induced [ Ca]i increase, suggesting that tyrosines at positions 443, 460, and/or 464 are important
Zhang et al., J Neurosci Res 2006 (Brain Ischemia...) : EPO also enhanced the CA1 level of brain derived neurotrophic factor
Miller et al., Cell Calcium 1994 : We have reported that erythropoietin induces a dose dependent increase in cytosolic calcium ([Cai]) in single human peripheral blood BFU-E derived erythroblasts which is specific for stage of differentiation and that this increase is modulated by erythropoietin through an ion channel permeable to Ca2+