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ING2 — TP53
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Zhang et al., Cancer Lett 2008
(Carcinoma, Hepatocellular...) :
Researches have shown that
ING2 can
activate p53 and p53 mediated apoptotic pathway involved in the hepatocarcinogenesis
Ythier et al., Lung Cancer 2010
(Carcinoma, Non-Small-Cell Lung...) :
Mechanistically, although p53 can regulate ING2 transcription and
ING2 enhances
p53 activity, no correlation between ING2 and p53 IHC status was observed