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BMP2 — POLDIP2

Text-mined interactions from Literome

Lemonnier et al., J Biol Chem 2004 : Activation of JNK and p38 induced by BMP-2 was blocked by the protein kinase C/protein kinase D ( PKC/PKD ) inhibitor Go6976 but not by the related compound, Go6983, a selective inhibitor of conventional PKCs. Associated with this inhibitory effect of Go6976, BMP-2 induced a selective and a dose dependent Ser916 phosphorylation/activation of PKD, which was also blocked by Go6976
Nørgaard et al., J Immunol 2010 (Multiple Myeloma) : Inhibition of Smad signaling and p38 MAPK signaling indicated that apoptosis of IH-1 cells is dependent on Smad signaling downstream of BMP, whereas the antiproliferative effect of BMP-2 on IH-1 cells also involves p38 MAPK signaling