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SOD1 — VEGFA

Text-mined interactions from Literome

Abid et al., FASEB J 2001 : VEGF stimulation of MnSOD was also inhibited by adenoviral mediated overexpression of catalase Cu, Zn-SOD and a dominant negative form of the small GTPase component of NADPH oxidase Rac1 ( Rac1N17 )
Fukuo et al., Circulation 2002 : In addition, recombinant VEGF induced an increase in the levels of SOD expression in ECs, and supernatant derived from nifedipine treated VSMCs enhanced NO production from ECs
Abid et al., J Biol Chem 2004 : In transient transfection assays, VEGF increased Mn-SOD promoter activity, an effect that was dependent on a second intronic NF-kappaB consensus motif ... In contrast, VEGF mediated induction of Mn-SOD was enhanced by the phosphatidylinositol 3-kinase (PI3K) inhibitor LY294002 and by dominant negative Akt and was decreased by constitutively active Akt
Grzenkowicz-Wydra et al., Mol Cell Biochem 2004 : Gene transfer of CuZn superoxide dismutase enhances the synthesis of vascular endothelial growth factor ... Overexpression of human SOD1 in mouse NIH 3T3 fibroblasts increased SOD activity, enhanced intracellular generation of H2O2 and significantly stimulated VEGF production as determined by increase in VEGF promoter activity, VEGF mRNA expression and VEGF protein synthesis ... The stimulatory effect on VEGF synthesis induced by SOD1 gene transfer was reverted by overexpression of human catalase
Wang et al., Oncogene 2005 (Adenocarcinoma...) : Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor
Guo et al., J Pharmacol Exp Ther 2007 : Polyethylene glycol-superoxide dismutase ( PEG-SOD ) markedly inhibited both the increases in VEGF expression and the proliferative effects of 20-HETE
Jiang et al., J Exp Med 2007 (Cardiomyopathy, Hypertrophic...) : HIF-1alpha coimmunoprecipitates with a Cu chaperone for superoxide dismutase-1 ( CCS ), and gene silencing of CCS, but not superoxide dismutase-1 , prevents IGF-1- or Cu-induced HIF-1alpha activation and VEGF expression
Zhao et al., Reprod Sci 2009 (Pre-Eclampsia) : The findings were ( 1 ) nephrin and GLEPP-1 were mainly expressed in glomerular podocytes ; ( 2 ) ezrin was expressed in both glomerular podocytes and tubular epithelial cells ; ( 3 ) compared to tissue sections from nonhypertensive and chronic hypertensive participants, nephrin and GLEPP-1 expressions were much reduced in tissue sections from preeclampsia and ezrin expression was reduced in podocytes ; ( 4 ) enhanced VEGF, Flt-1, and nitrotyrosine, but reduced CuZn-SOD , expressions were observed in both glomerular podocytes and endothelial cells in tissue sections from preeclampsia ; and ( 5 ) the expression pattern for nephrin, GLEPP-1, ezrin, VEGF , Flt-1, and CuZn-SOD were similar between tissue sections from nonhypertensive and chronic hypertensive participants
Mali et al., Neurobiol Dis 2010 (Amyotrophic Lateral Sclerosis) : VEGF up-regulation by G93A superoxide dismutase and the role of malate-aspartate shuttle inhibition ... Here we report that expression of G93A-hSOD1 fused with green fluorescent protein in NSC-34 cells enhanced VEGF expression and levels of VEGF and its upstream regulator hypoxia-inducible factor ( HIF-1alpha )
Chen et al., Asian Pac J Trop Med 2012 (Diabetes Mellitus, Experimental) : Puerarin enhances superoxide dismutase activity and inhibits RAGE and VEGF expression in retinas of STZ induced early diabetic rats
El-Remessy et al., PloS one 2013 : The superoxide dismutase ( SOD ) mimetic tempol blocked diabetes induced permeability and uPAR expression in rats and the cell permeable SOD inhibited HG-induced expression of uPAR and VEGF in REC