Chang et al., Int J Mol Med 2011
(Peritoneal Fibrosis) :
The objective of the present study was to investigate the role of NADPH oxidase dependent formation of reactive oxygen species ( ROS ) in the angiotensin II (Ang II) induced epithelial-mesenchymal transition (EMT) and in the accumulation of extracellular matrix ( ECM ) in rat peritoneal mesothelial cells ( RPMCs ) ... In conclusion, NADPH oxidase dependent formation of ROS mediates Ang II dependent EMT and accumulation of ECM in rat peritoneal mesothelial cells
Ju et al., American journal of physiology. Renal physiology 2012
(Albuminuria...) :
The present study established that activation of NADPH oxidase plays a crucial role in diabetes induced oxidative stress, glomerular hypertrophy, and ECM molecule expression